Microplastics Invade the Brain – How Can We Break Free from Plastic Anxiety?
I. Plastic Crisis, Refreshed on a Timer
Since joining an environmental agency a few years ago, I’ve become especially attentive to the materials in everyday products, and often – deliberately or not – warn friends about potential hazards. Over time, whenever friends come across related stories, they send them to me for a fact-check, and the questions that come up most concern plastic: “Can I store kimchi in a plastic container?” “Is it true that all black plastic is recycled plastic?”
I’m sure I’m not alone in feeling this way. News about the dangers of plastic seems like a system notification that Earth Online respawns on a regular schedule – every so often, there it is again.
And every time a large marine animal washes up dead on a beach, the post-mortem invariably reveals “a stomach full of plastic bags”; go hiking or trekking and you’ll spend the whole route picking up litter, yet the mountains never run out of rubbish. After enough anxiety, it curdles into irritation. Some people stop reading these reports altogether, figuring, “I can only worry – I can’t change a thing. I may as well not look.”
This latest “microplastics have entered the brain” story triggered another round of panic among friends.
I wanted to reassure them: “They’ve simply detected plastic – it doesn’t necessarily harm the brain.” But the words were barely out of my mouth when I remembered that researchers have already found numerous links between microplastics and human disease. In the end, I gave a rather feeble reply – “Microplastics are in the air anyway; it’s not something we can completely shut out no matter how hard we try” – which only made my friends more anxious.


Deep down, we know that the proliferation of plastic is a serious problem, yet for non-specialists it is extremely difficult to understand exactly what makes it harmful. We can barely tell which everyday items are made of plastic and which are not. A danger this pervasive inspires less fear than helplessness, anxiety and frustration.
At the height of my plastic anxiety, I wondered: is it even possible to avoid plastic in daily life? I joined a few short-term practice groups where we logged the amount of plastic waste each person generated every day and discussed ways to reduce it. We found that with great care you could manage one or two days of “zero plastic”, but not a single person could sustain it for 21 days. The day I finally broke the streak, a box of peaches arrived at my door. I tore off the plastic tape, and a dozen peaches tumbled out, each wrapped in foam mesh netting. That day my log read: “Generated an uncountable amount of plastic waste today.”
I couldn’t fault the fruit farmers for bagging their produce – every bruised fruit meant a loss to them, and the same applies for buying at a physical supermarket.

But does “living with plastic” truly mean we are helpless in the face of the problem? Is there not a second-best option – a way to protect ourselves as much as possible within the sphere we can actually control?
For me, taking the time to understand what plastic actually does to our health was the first step in facing my “plastic anxiety”.
II. What Are the Health Dangers of Plastic, Exactly?

The main sources of health risk to ordinary people are microplastics and plastic additives. The more fragile and prone to damage a plastic is, the greater the quantity of these two it releases.
Microplastics are plastic particles smaller than 5 millimetres in diameter. A growing body of research suggests that microplastics may pose various health risks. A study published last year found that, compared with patients who had no detectable microplastics in their carotid arteries, carotid artery plaque containing microplastics was associated with a 3.53-fold increase in the risk of heart attack, stroke or all-cause mortality. Meanwhile, research on other organisms has shown that microplastics can trigger inflammation, cause foetal malformation and impair fertility. The highly porous physical structure of microplastics also gives them the capacity to adsorb heavy metals, antibiotics and other substances from the environment.

Many additives are toxic in their own right, the most prevalent being phthalates and bisphenol A.
Phthalates (PAEs) are generally used as plasticisers to improve the pliability of plastics. Soft, flexible plastic products typically contain a higher proportion of plasticisers. Phthalates encompass a very large class of compounds; their content in plastic typically ranges from 10% to 60%, and can reach as high as 90%.
Bisphenol A (BPA) is a resin monomer used in a wide range of applications: epoxy resin (food containers, beverage bottles, can linings), receipt paper, plastic water bottles, spectacle lenses, erasers and many more.
Because both of these substances share a structural similarity with oestrogen, they have both been found to disrupt the endocrine system.

III. Tips for Avoiding Toxic Plastics
Tip One: Check the resin identification codes and avoid PVC and PS

The first thing any newcomer to the world of plastic should do is learn to read resin identification codes. These codes indicate the type of plastic and its intended use. Once a plastic is used outside its normal conditions, it can become hazardous – most people already have a basic sense of this; for instance, a PET water bottle should never be heated.
Among them, two plastics are particularly prone to releasing toxins and require extra caution in everyday use:
Plastic No. 3 – PVC (polyvinyl chloride) could be called the most dangerous plastic of them all. The reason is that pure PVC is far too brittle; large quantities of additives must be blended in to achieve workable performance. In soft PVC products such as shower curtains, plasticiser content can reach 60–70%. However, PVC monomers cannot bond stably with these additives, so once the product is manufactured, the additives begin leaching out at varying rates. This is why most PVC products carry a persistent “plastic-and-glue” smell – it is the odour of the escaping additives.
The most common PVC products include: plastic shower curtains, single-use packaging bags, plastic water pipes, stone plastic composite (SPC) flooring, cling film, various plastic cards such as credit cards, signage, placemats, cleaning brushes, powder puffs, children’s toy balls, stationery and raincoats.

Plastic No. 6 – PS (polystyrene) Also known as foamed plastics, expanded plastics, or Styrofoam, PS plastic is now most commonly seen in the foam-insulated shipping boxes used for transporting goods.
The monomer in PS (polystyrene) – styrene – is itself a carcinogen. Although PS plastic itself is non-toxic, it is extremely heat-sensitive: its safe use temperature is only 70–90 °C. At around 70 °C it begins to deform and collapse, releasing styrene and various additives.
Expanded polystyrene food containers, once commonplace, were already banned in China in 2020 due to their high risk. A search on Taobao will tell you that sales are prohibited under the “plastics ban” – and yet such products can still be found on the market.

Tip Two: Use Plastic for Food Packaging with Caution
But these containers are all rather heavy, and an office worker lugging them on the commute feels like they are being punished. As a practical fallback, at least bringing a relatively safe PP (polypropylene) lunch box is better than nothing. By comparison, the risk they pose is far lower than that of the single-use containers provided with takeaway food.



In addition, no matter what type of plastic packaging your food comes into contact with, you should always follow the rule of “no alcohol, low oil, never piping hot”– that is, do not store food containing alcohol or high amounts of fat in plastic containers, and do not use plastic containers for high-temperature heating.
Although the theoretical deformation temperature of the PP (polypropylene) used in most plastic lunch boxes is 120 °C, steam can reach this critical threshold, and heated oil can easily exceed 170 °C. It is therefore best to avoid placing plastic lunch boxes directly in a steamer or microwave for heating.
In fact, PP (polypropylene) is not an ideal freezer container either, because it becomes brittle below 0 °C and is extremely prone to shattering if dropped. Before I knew anything about plastics, I bought a batch of PP airtight containers for home use – most of them have already been smashed, and I am gradually replacing them.
If you absolutely must order a takeaway, try to prioritise dishes served at a lower temperature and with less oil, such as cold noodles or salad, or dishes with minimal sauce, such as hand-shredded chicken rice.

Tip Three: Do Not Reuse Single-Use Plastic Products for the Sake of Saving Money

By contrast, pricier durable plastics tend to be more stable and safer, because their standard testing protocols include requirements such as “after 1,000 washes, the quantity of leached substances does not pose a health risk” and “after 1,000 abrasions, the surface remains intact without crumbling.”
Furthermore, many single-use products do not undergo the necessary cleaning and sterilisation during production. Even if they are tableware, complex dust particles and bacteria will very likely end up in our mouths along with the product. The Cantonese custom of rinsing tableware with tea before dining out is not entirely just superstitious comfort. If you have handled delivery packaging or other single-use plastic products, it is advisable to wash your hands afterwards.
In truth, when it comes to “use and toss” products, sellers care even less than consumers do about quality and safety. The issues concerning disposable underwear and sanitary towels recently exposed on 3·15 Consumer Rights Day confirm this point.
Many people do not realise that sanitary towels are also plastic products. The top layer of a traditional sanitary towel is either a perforated film (mesh-textured) or non-woven fabric (cotton-feel); fluff pulp is used only in the middle absorbent layer, and some products also contain superabsorbent polymers. The bottom layer is PE (polyethylene) film for leak protection. Liquid sanitary pads, meanwhile, have even less to do with plant fibres: their absorbent core is a patented polyacrylate foam, which is itself a type of plastic.

I switched to a reusable silicone menstrual cup several years ago. Considering that, to this day, there is still no reassuring national standard for sanitary towels, readers who are concerned may wish to consider this option and take charge of cleaning and sterilisation themselves.
In addition, many single-use plastic products are not labelled with their plastic type, and identifying them by sight is virtually impossible. If you cannot tell what something is made of, try not to use it proactively. If you receive one passively, you can use it a limited number of times, but avoid using it as a food container.

Tip Four: Ditch Cling Film and Food Storage Bags
What is more, their “freshness-preserving” function is not all it is cracked up to be. Cling film and food storage bags have no inherent antibacterial or preservative properties; they work mainly by creating a barrier against air and contaminants. But sometimes they backfire – I am sure most people are all too familiar with vegetable leaves that have gone to mush inside a food storage bag. Vegetables I put straight into a fridge drawer without any bag keep perfectly well for half a month.

For food that needs to be portioned and stored, stainless steel or PP (polypropylene) airtight containers are more than up to the task. Stainless steel freezes meat more effectively than food storage bags, and rigid materials will not freeze directly onto the food the way film does. Even a sturdy airtight bag is more robust than thin film.
If you feel you cannot do without either of these, I strongly advise at least avoiding PVC, and never heating them or letting them come into contact with oily foods when you do use them. Our household still uses airtight bags made primarily of PE (polyethylene), but I virtually never store oily food in them; pickled vegetables are always kept in glass airtight containers.

Tip Five: Turn Your Back on Non-Woven Fabric, Laundry Capsules, and Other “Hidden” Plastics



To me, deliberately generating enormous quantities of microplastics in exchange for a modicum of convenience is simply not a trade worth making. Moreover, because these products come in fixed doses, they are prone to overuse, and they cost considerably more than conventional detergents.
Four: The Safe Distance Between Us and Plastic
But do not let this fill you with anxiety. After all, “resolving plastic pollution” is a highly specialised public issue, and responsibility for it should rest with governments, businesses, and experts. When you start worrying that personal change cannot solve the problem, yet still feel an overwhelming sense of anxiety and helplessness, you can tell yourself, “I am not the primary party responsible for pollution,” and try to urge those who truly should make changes to fulfil their duties.
What remains for us to do is maintain a safe distance from plastic and use plastic products within safe, limited boundaries. Shifting your mindset matters: stop treating plastic products as disposable “convenience items” and see them instead as durable goods with specific use parameters. Just as metal cutlery should not go in a microwave and overglaze-decorated ceramics carry a risk of heavy metals, plastic can be used just as metal and ceramics are – but you need to mind the setting and stay safe. The truly dangerous thing is being surrounded by plastic in daily life yet knowing nothing about it.
Modern society is riddled with so many hazards to human health: antibiotic misuse, second-hand smoke, cooking-oil contamination… Plastic is simply one of the most commonplace. At the very least, the evidence shows that ingesting microplastics will not kill you on the spot, nor will you instantly become a “plastic person.” There is still hope for peaceful coexistence with plastic.
References
[1] Haipeng Huang et al., Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioural abnormalities. Sci. Adv. 11, eadr8243 (2025). DOI: 10.1126/sciadv.adr8243
[2] Wudu Xianfeng, Foodthink. Detox Dossier: How Much Do You Know About Food Packaging? [R]. 2020.
[3] BFFP. Plastic Atlas: The World of Synthetic Polymers – Facts and Data [R]. 2019: 11, 17, 34–35.
[4] From Pollution to Solution: A Global Assessment of Marine Litter and Plastic Pollution [R]. United Nations Environment Programme, 2021. 1.1 https://www.gdr-po.cnrs.fr/docs/UNEP_2021.pdf
[5] Marfella, R., Prattichizzo, F., Sardu, C., Fulgenzi, G., Graciotti, L., Spadoni, T.,… & Paolisso, G. (2024). Microplastics and nanoplastics in atheromas and cardiovascular events. New England Journal of Medicine, 390(10), 900-910.
[6] Chen, J., Chen, G., Peng, H., Qi, L., Zhang, D., Nie, Q.,… & Luo, W. (2023). Microplastic exposure induces muscle growth but reduces meat quality and muscle physiological function in chickens. Science of The Total Environment, 882, 163305.
[7] He Yan, Wang Jing, Zhao Man, et al. Adsorption Behaviour of Biodegradable Microplastics toward Sulfadiazine [J/OL]. Environmental Science and Technology, 1-15 [2024-04-15]. http://kns.cnki.net/kcms/detail/42.1245.x.20240330.1555.008.html.
[8] 5 Gyres Institute. BETTER ALTERNATIVES 3.0 [R]. 2023. https://www.5gyres.org/betteralternatives.
[9] Fackelmann, G., Pham, C. K., Rodríguez, Y., Mallory, M. L., Provencher, J. F., Baak, J. E., & Sommer, S. (2023). Current levels of microplastic pollution impact wild seabird gut microbiomes. Nature Ecology & Evolution, 7(5), 698-706.
[10] Hu Hongmei, Li Tiejun, Zhu Yingjie, et al. Research Progress on Phthalate Ester Contamination and Detection Methods [J]. Journal of Food Safety and Quality, 2021, 12(21): 8573-8581. DOI: 10.19812/j.cnki.jfsq11-5956/ts.2021.21.039.
[11] Liu Chunhong, Sun Yuanming, Yang Yichao, et al. Contamination and Exposure Assessment of Phthalate Ester Plasticizers [J]. Modern Food Science and Technology, 2012, 28(03): 339-341+338. DOI: 10.13982/j.mfst.1673-9078.2012.03.033.
[12] Wang Yongfeng, Yu Jingyuan, Zhang Hao. Sources, Distribution, and Health Risks of Bisphenol Compounds in Environmental Media in China: A Review [J/OL]. Shandong Science, 1-15 [2025-03-15]. http://kns.cnki.net/kcms/detail/37.1188.N.20250313.1424.004.html.
[13] QADEER A, KIRSTEN KL, AJMAL Z, et al. Alternative plasticizers as emerging global environmental and health threat: Another regrettable substitution? [J]. Environmental Science & Technology, 2022, 56(3): 1482-1488. DOI: 10.1021/acs.est.1e08365.
[14] EUR. Commission Regulation (EU) No 10/2011 [Z]. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A02011R0010-20250120.2025-01-20.
[15] GB/T 26572-2011, Limits of Restricted Substances in Electrical and Electronic Products [S].
[16] National Standards of the People’s Republic of China. Announcement on the Approval and Publication of 109 National Standards Including Manganese-Silicon Alloy and 4 Amendment Sheets to National Standards [OL]. https://std.sacinfo.org.cn/gnoc/queryInfo?id=E2F76A3B449808FD198E132C41ADD96E,2024-6-29.
[17] State Administration for Market Regulation. Guiding Opinions on Prevention and Control of Plasticizer Contamination Risks in Food [OL]. https://www.samr.gov.cn/zw/zfxxgk/fdzdgknr/spscs/art/2023/art_904e69afd8ea41c69e55509556db15f0.html,2019-11-03.
[18] United States Consumer Product Safety Commission. Phthalates Business Guidance [Z]. https://www.cpsc.gov/Business–Manufacturing/Business-Education/Business-Guidance/Phthalates.
[19] Hua Yingdi, Xu Yiping, Zhao Gaofeng, et al. Environmental Migration, Toxicity Testing and Risk Screening of Plastic Additives: Progress and Challenges [J]. Asian Journal of Ecotoxicology, 2024, 19(02): 93-111.
[20] Annie Leonard. The Story of Stuff [M]. Zhejiang People’s Publishing House, 2014-3.
[21] Greenpeace. Is Polystyrene Number 6 Plastic? Is Polystyrene (PS) Toxic? Is It Recyclable? [OL]. https://www.greenpeace.org/taiwan/update/36710/%E4%BF%9D%E9%BA%97%E9%BE%8D%E6%98%AF6%E8%99%9F%E5%A1%91%E8%86%A0%EF%BC%9F%E8%81%9A%E8%8B%AF%E4%B9%99%E7%83%AF%EF%BC%88ps%EF%BC%89%E6%9C%89%E6%AF%92%EF%BC%9F%E5%8F%AF%E5%9B%9E%E6%94%B6%E5%97%8E/.2023-7-6.
[22] National Development and Reform Commission. Opinions of the National Development and Reform Commission and the Ministry of Ecology and Environment on Further Strengthening Plastic Pollution Control [Z]. https://www.mee.gov.cn/xxgk2018/xxgk/xxgk10/202001/t20200120_760495.html.2020-1-19.
[23] Alonso-López O, López-Ibáñez S, Beiras R. Assessment of Toxicity and Biodegradability of Poly(vinyl alcohol)-Based Materials in Marine Water. Polymers (Basel). 2021 Oct 29; 13(21): 3742. doi: 10.3390/polym13213742. PMID: 34771298; PMCID: PMC8588384.
[24] Suzuki, M., Tachibana, Y. & Kasuya, Ki. Biodegradability of poly(3-hydroxyalkanoate) and poly(ε-caprolactone) via biological carbon cycles in marine environments. Polym J 53, 47–66 (2021). https://doi.org/10.1038/s41428-020-00396-5
[25] Lianhe Zaobao. Study: Microplastics in Human Brain Samples Have Increased by 50% Over Eight Years [OL]. https://www.zaobao.com.sg/news/world/story20240901-4534890.2024-09-01.
[26] CCTV.com. Follow-up on “Tanker Truck Rollover Causing Crude Benzene Leak” in Yongzhou, Hunan: Water Quality Sections on All Cross-sections Remain Continuously Stable and Compliant; Emergency Response Terminated [OL]. https://news.cctv.com/2025/02/09/ARTIXRe9KRUkrpK32wRTqfGW250209.shtml.2025-02-09.
[27] Ministry of Ecology and Environment. Case Study: Secondary Sudden Environmental Incident from Crude Benzene Tanker Rollover and Leak in Xinjiang, Shanxi [OL]. https://www.mee.gov.cn/ywgz/hjyj/yjxy/201912/t20191228_752089.shtml.2019-12-28.
[28] Zhejiang Provincial Administration for Market Regulation. How to Properly Choose Sanitary Towel Products? [OL]. https://zjamr.zj.gov.cn/art/2021/12/15/art_1228969910_59011990.html.2021-12-15.
[29] Always. Always FlexFoam: Made Differently, Works Differently [OL]. https://www.always.com/en-us/about-us/what-are-always-flexfoam-pads-made-of.
[30] Jiemian News. 3·15 Gala Exposes Disposable Underwear Made by Hand Without Sterilisation, Implicating Langsha, Beizhiyan, Chuyisheng and Other Brands | 3·15 Special Report [OL]. https://mp.weixin.qq.com/s/k3VCukMVWur0V8dBerR3Sg.2025-03-15.
[31] Jiemian News. 3·15 Gala Exposes Sanitary Towels and Nappies Made from Waste and Garbage, Implicating Miffy and Other Brands | 3·15 Special Report [OL]. https://mp.weixin.qq.com/s/FWQwEjPGXR3ghsJUR9iyVg.2025-03-15.
[32] Hernandez LM, Xu EG, Larsson HCE, Tahara R, Maisuria VB, Tufenkji N. Plastic Teabags Release Billions of Microparticles and Nanoparticles into Tea. Environ Sci Technol. 2019 Nov 5; 53(21): 12300-12310. doi: 10.1021/acs.est.9b02540. Epub 2019 Sep 25. PMID: 31552738.

Editor: Wang Hao





